Dictionary

Word


Content on this page requires a newer version of Adobe Flash Player.

Get Adobe Flash player

Nano-Biology and Application Unit

 

Tel:(84) 24-35579354 / (84)24- 35579515

Address: Room 406-T2 Block, 441B-T8 Block - VNU University of Science

334 Nguyen Trai, Thanhxuan, Hanoi, Viet Nam

A-MagPure FFPE DNAnano kit consistingof silica-coated Fe3O4 nanoparticlesand buffers for extraction of DNA from Formalin Fixed Paraffin Embedded tissue
B-Schema of Protein drug in agarose-glucan delivery system

Curently employed staffs

Head: Assoc. Prof. Dr. Nguyen Thi Van Anh, Lecturer

Education: PhD 2004, Tohoku University, Japan

Specification: Molecular Biology

Tel: (84)2435579254 

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Assoc. Prof. Dr. Bui Thi Viet Ha, Lecturer

Education: PhD 2007 VNU University of Science, Hanoi

SpecificationMicrobiology

Tel: (84) 24 38588856

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Assoc. Prof. Dr. Hoang Thi My Nhung, Lecturer

Education: PhD 2008, Grenoble I University, France

Specification: Cell Biology

Tel: (84)2435588478 

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Dr. Pham Thi Thu Huong, Lecturer

Education: PhD 2013, Chungnam National University, Daejeon, Korea

Specification: Biochemistry

Tel: (84)24 35579515 

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Research Interests and activities

Our mission is to (i) study and develop bio-nano materials for diagnostics and drug delivery; (ii) using genetic, protein and enzyme technologies to create products applicable in the field of food industry, agriculture, and using anaerobic bacteria isolated from Vietnam via dark fermentationto produce biohydrogen from various renewable feed-stocks. Research activities include:     

Develop novel and effective nano-bio materials for diagnostics and drug delivery purpose based on bioengineering and nanotechnology components. Such components include antibody and magnetic nanoparticles, fluorescent probes, beta-glucannanogel complexes carrying of tumor necrosis factor alpha (TNF-a) inhibitors to apply on treatment of rheumatoid arthritis disease; polymeration of some antitumor compounds which is sensitivity to pH tumor.

Development of in-vitro and in vivo assays to screen anti-cancer bioactive compounds and to evaluate the functions of nano particles in drug delivery and thermotherapy.

Research on hydrogen production from dark fermentation of anaerobic bacteria by using various renewable feed-stocks.

Development of probiotics containing Bacillus sp. spores producing carotenoids as novel feed supplements for shrimps, using enzyme technology to produce arabinoxylan from biobran for use as functional foods. Those products are developed for technology transfer to manufactures.

Selected research projects

Production of functional food containing arabinoxylan using enzyme technology (2016-2018). Ministry of Industry and Trade, code: SXTN.0416/CNSHCB. PI: Assoc. Prof. Dr. Nguyen Thi Van Anh.

Development of DNA and RNA extraction kits for formalin-fixed paraffin-embedded (FFPE) tissues (2016-2018). Vietnam National University, code: QG.16.22. PI: Assoc. Prof. Dr. Nguyen Thi Van Anh.

Establishment of a process for biohydrogen production by utilizing mesophilic anaerobic bacteria isolated in Vietnam (2016-2018). Vietnam National University, code: QG.16.03, PI: Assoc. Prof. Dr. Bui Thi Viet Ha.

Synthesis of biocompatible nano particles containing magnetic cores for diagnostic and cancer treatment, code ĐT.NCCB-ĐHƯD.2012-G/08. PI: Prof. Dr. Sci. Nguyen Xuan Phuc (member: Assoc. Prof. Hoang Thi My Nhung).

Research on making of schizophyllan nanogels (SPG) carrying of tumor necrosis factor alpha (TNF-a) inhibitors to apply on treatment of rheumatoid arthritis disease (2016-2018). Vietnam National University, code: KLEPT.16.01, PI: Dr. Pham Thi Thu Huong.

Selected Publications

Nguyen MH, Nguyen HN, Nguyen TH, Nguyen TVA, Phan TN, Nguyen BK, Nguyen LT, Nguyen HL (2017) Synthesis of SiO2-Coated Fe3O4 Nanoparticles Using Ultrasound and Its Application in DNA Extraction from Formalin-Fixed, Paraffin-Embedded Human Cancer Tissues. Journal of Electronic Material, doi:10.1007/s11664-017-5282-6. (ISI; IF = 1,29) .

- Sakchaisri Jack, Sunok Kim, HJ Ah, Soungnak Kuyn, Lee KuyngHo, Chanmi Park, Thimmeogowda NR, Thi Thu Huong Pham, Jang Je Hak, Kyunglee, BoY Kim (2017) Anticancer Activity of a Novel Small Molecule Tubulin Inhibitor STK899704. PLoS One 12(3):e0173311 (ISI; IF = 3.54)

- Ngo TH, Nguyen TNT, Nguyen MQ, Tran VA, Nguyen ATV, Nguyen DV, Tran MT, Nguyen LT, Nguyen AH, Phan TN, (2016) Screening of pigmented Bacillus aquimaris SH6 from the intestinal tracts of shrimp to develop a novel feed supplement for shrimp. J. Appl Microbiol Doi: 10.111/jam.13274. (ISI; IF = 2,14)

- Nhung Thi My Hoang, Thuong Thien Phuong, Trang Thi Nhu Nguyen, Yen Thi Hai Tran, Anh Thi Nguyen Ngoc, Thanh Lai Nguyen, Khanh Thi Van Bui (2016) In vitro characterization of derrone as an Aurora Kinase inhibitor. Biol Pharm Bull. 39, 935-945. (ISI; IF = 1.57)

- Ha Phuong Thu, Nguyen Hoai Nam, Le Quang Duong, Nguyen Thi Tham, Bui Thuc Quang, Ha Thi Minh Thi, Do Hai Doan, Hoang Thi My Nhung (2016) Targeting effect of folate on cancer cell through curcumin carrier nano-system. International Journal of drug delivery 6, 351-358. (ISI; IF = 1.02).

- Nguyen Thi Hong Hue, Pham Duc Ngoc, Tran My Hanh, Ngo Anh Tien, Bui Thi Viet Ha (2016) Effects of environmental parameters on hydrogen production of strain Clostridium beijerinckii CB3 isolated in North of Vietnam under anaerobic condition, VNU Journal of Science, Natural Sciences and Technology, 32, No.1S, 258-268.

- Đỗ Thị Hồng Thu, Đỗ Thị Hoàng Kim, Nhữ Văn Hùng, Trần Thị Mỹ, Nguyễn Thị Vân Anh, Phạm Thị Thu Hường (2016)Evaluation on the transcription level of some genes related to the shrimp innate immune responses to the VP28 antigen of White Spot Syndrome Virus. VNU Journal of Science, Natural Sciences and Technology, Vol9 (10), p54-59 (ISSN 1859-4794).

- Nguyen ATV, Nguyen DV, Tran MT, Nguyen LT, Nguyen AH, Phan TN (2015) Isolation and characterization of Bacillus subtilis CH16 strain from chicken gastrointestinal tracts for use as a feed supplement to promote weight gain in broilers. Lett Appl Microbiol 60, 580-588. (ISI; IF = 1,68)

- The Thu Pham, Van Thuoc Chu, Thi Viet Ha Bui, Thanh Thuy Nguyen, Quang Huy Tran, Thi Ngoc Mai Cung, Corinme Bouvier, Justine Brune, Sebastien Villeger, Thierry Bouvier. Yvan Bettarel (2015) Coral-associated viruses and bacteria in the Ha Long Bay, Vietnam. Aquatic Microbial Ecology 76, 149-161. (ISI; IF = 2.109)

- Pham Thu Trang, Pham The Thu, Bui Thi Viet Ha, 2015. Isolation and screening for probiotics producing carotenoids in coral mucus layer in two archipelagoes, Cat Ba and Long Chau - Vietnam. VNU Journal of Science, Natural Sciences and Technology, 31, 445-452